Anzergent

Anzergent

Anzergent is a non-ionic detergent known for its amphiphilic nature and low critical micelle concentration (CMC), making it advantageous for solubilizing membrane proteins at low detergent concentrations. This unique combination minimizes potential interference in subsequent applications. Studies have highlighted the importance of low CMC detergents in maintaining membrane protein stability, underscoring the relevance of Anzergent in this context.The low CMC of Anzergent is particularly advantageous for solubilizing membrane proteins at low detergent concentrations, as it allows for the stabilization of hydrophobic cargoes in extremely diluted conditions, minimizing interference in subsequent applications. Additionally, Anzergent  has been used in a 'dual-detergent strategy' for the cost-effective purification of membrane proteins, demonstrating its practical advantages in this context.Non-ionic detergents like Anzergent have a hydrophilic head group that is uncharged, making them suitable for breaking lipid-lipid and lipid-protein interactions. They are often referred to as non-denaturing detergents and are used to isolate biologically active membrane proteins.

Anzergent's amphiphilic nature and low CMC make it particularly advantageous for solubilizing membrane proteins at low detergent concentrations, minimizing potential interference in subsequent applications and contributing to the cost-effective purification of membrane proteins.

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